Startup Manager not compatible with Windows 10
The Startup Manager isn't compatible with Windows 10. In Windows 10 you can disable apps startup in the Task Manager (set to disabled). But unfortunately the disabled items show up as enabled in Glary Utilities' Startup Manager. It needs some rewriting.

Thank you for your letter.
We are so sorry for the inconvenience.
When you download it, please try to stop running your anti-virus software for a while.
Please try to uninstall the current version on your pc. Please make sure all the files under “C:\Program Files\Glary Utilities 5” are deleted. Then restart the PC.
Then download and install a new copy of our program(not the previous one saved on your pc). That may solve this problem.
GU5 version download link:https://download.glarysoft.com/gu5setup.exe
Or GU5 Pro version download link:https://download.glarysoft.com/gup5setup.exe
-What is your operating system: win10 32bit or 64bit?
If you meet any problem when you install or use it, screenshots would also be very helpful to understand the problem at a glance. Thanks.